Reduction Surgery of Giant Hemifacial Neurofibromas: A Case Report

Neurofibromatosis type 1 (NF-1), first described by Von Recklinghausen (1882), is an autosomal dominant disease caused a spectrum of mutations in NF-1 gene. We reported case giant facial neurofibromas 26 years old male patient without family history neurofibromatosis 1. Features typical neurofibroma, including enlarged nerve fascicle composed elongated nuclei and scant cytoplasmic cells, were identified. Excision was performed with preservation parotid duct. The mass weight about 5,5 kg. There some challenges during the procedure, such as bleeding, hypovolemia, vital structure.